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Shigeru Horiguchi Selected Research

Transcription Factor 3

5/2016Loss of Runt-related transcription factor 3 induces resistance to 5-fluorouracil and cisplatin in hepatocellular carcinoma.
8/2013Loss of runt-related transcription factor 3 induces gemcitabine resistance in pancreatic cancer.
12/2012Runt-related transcription factor 3 reverses epithelial-mesenchymal transition in hepatocellular carcinoma.
9/2011Restored expression of the tumor suppressor gene RUNX3 reduces cancer stem cells in hepatocellular carcinoma by suppressing Jagged1-Notch signaling.
1/2011Loss of runt-related transcription factor 3 expression leads hepatocellular carcinoma cells to escape apoptosis.

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Shigeru Horiguchi Research Topics

Disease

27Neoplasms (Cancer)
10/2022 - 01/2011
11Pathologic Constriction (Stenosis)
10/2022 - 08/2013
8Hepatocellular Carcinoma (Hepatoma)
06/2020 - 01/2011
6Stomach Neoplasms (Stomach Cancer)
04/2022 - 01/2011
6Pancreatic Neoplasms (Pancreatic Cancer)
11/2019 - 08/2013
5Pancreatitis
03/2022 - 01/2016
4Carcinoma (Carcinomatosis)
03/2022 - 07/2015
2Neoplasm Metastasis (Metastasis)
04/2022 - 06/2021
2Gallbladder Neoplasms (Gallbladder Cancer)
10/2021 - 01/2019
2Neuroendocrine Tumors (Neuroendocrine Tumor)
10/2018 - 08/2016
1Gallstones (Gallstone)
03/2022
1Adenocarcinoma
12/2021
1Actinomycosis
12/2021
1False Aneurysm (Pseudoaneurysm)
07/2021
1Venous Thrombosis (Deep-Vein Thrombosis)
07/2021
1Rupture
07/2021
1Colonic Neoplasms (Colon Cancer)
05/2021
1Body Weight (Weight, Body)
05/2021
1Acinar Cell Carcinoma
01/2021
1Fatigue
01/2021
1Abdominal Pain (Pain, Abdominal)
01/2021
1Anorexia
01/2021
1Dermatitis
01/2021
1Communicable Diseases (Infectious Diseases)
01/2021
1Melanoma (Melanoma, Malignant)
01/2021
1Hypotension (Low Blood Pressure)
12/2019
1Pancreatic Diseases (Pancreatic Disease)
12/2019
1Pancreaticobiliary Maljunction
01/2019
1Mucinous Adenocarcinoma (Mucinous Carcinoma)
01/2019
1Aseptic Meningitis
11/2018
1Osteomyelitis
11/2018
1Cavernous Sinus Thrombosis
11/2018
1Headache Disorders (Headache Syndromes)
11/2018
1Epithelioid Hemangioendothelioma
10/2018
1Nausea
10/2018
1Primitive Neuroectodermal Tumors (PNET)
10/2018
1Cholangiocarcinoma
08/2018
1Peritonitis
01/2018
1Cholangitis
01/2018
1Hemorrhage
01/2018

Drug/Important Bio-Agent (IBA)

5Proteins (Proteins, Gene)FDA Link
04/2022 - 08/2013
5Cisplatin (Platino)FDA LinkGeneric
10/2018 - 11/2015
5Transcription Factor 3IBA
05/2016 - 01/2011
3Biomarkers (Surrogate Marker)IBA
10/2022 - 03/2017
3Diclofenac (SR 38)FDA LinkGeneric
05/2021 - 01/2016
3Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
05/2021 - 01/2016
2Laminin (Merosin)IBA
04/2022 - 06/2021
2Anti-Bacterial Agents (Antibiotics)IBA
12/2021 - 01/2021
2DNA (Deoxyribonucleic Acid)IBA
05/2021 - 03/2017
2EnzymesIBA
01/2021 - 06/2016
2PlatinumIBA
01/2021 - 08/2018
2Fluorouracil (Carac)FDA LinkGeneric
10/2018 - 05/2016
2GemcitabineFDA Link
08/2018 - 08/2013
2MetalsIBA
01/2017 - 06/2015
2Ethanol (Ethyl Alcohol)IBA
08/2016 - 01/2016
1laminin 10IBA
04/2022
1GTP Phosphohydrolases (GTPases)IBA
04/2022
1MicroRNAs (MicroRNA)IBA
10/2021
1Warfarin (Coumadin)FDA LinkGeneric
07/2021
1Protein Isoforms (Isoforms)IBA
06/2021
1IntegrinsIBA
06/2021
1Formaldehyde (Formol)FDA Link
05/2021
1ParaffinIBA
05/2021
1Immune Checkpoint InhibitorsIBA
01/2021
1Irinotecan (Camptosar)FDA LinkGeneric
01/2021
1IpilimumabIBA
01/2021
1Prednisolone (Predate)FDA LinkGeneric
01/2021
1Ceftriaxone (Ceftriaxon)FDA LinkGeneric
01/2021
1NivolumabIBA
01/2021
1Propofol (Diprivan)FDA LinkGeneric
12/2019
1B7-H1 AntigenIBA
11/2019
1AntibodiesIBA
11/2019
1phytobacteriomycin (PBM)IBA
01/2019
1Indicators and Reagents (Reagents)IBA
10/2018
1Leucine (L-Leucine)FDA Link
10/2018
1Streptozocin (Streptozotocin)FDA Link
10/2018
1DipeptidesIBA
10/2018
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
10/2018
1Amyloid Precursor Protein Secretases (beta-Secretase)IBA
10/2018
12'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA
10/2018
1Carcinoembryonic AntigenIBA
08/2018
1Sorafenib (BAY 43-9006)FDA Link
08/2018

Therapy/Procedure

11Stents
03/2022 - 08/2013
7Drug Therapy (Chemotherapy)
12/2021 - 07/2015
3Pancreaticoduodenectomy
03/2022 - 08/2013
3Therapeutics
01/2021 - 08/2016
2Self Expandable Metallic Stents
10/2022 - 07/2015
2Pancreatectomy
12/2021 - 01/2016
2Catheters
07/2021 - 08/2013
2Liver Transplantation
12/2016 - 01/2016
1Endoscopic Sphincterotomy
03/2022
1Splenectomy
12/2021
1Gastrectomy
12/2021
1Rectal Administration
05/2021
1Immunotherapy
01/2021
1Intravenous Anesthesia
12/2019
1Laparoscopic Cholecystectomy
01/2019
1Cholecystectomy
01/2019
1Tooth Extraction (Tooth Extractions)
11/2018
1Cannula
01/2018